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Indications for injection in glenohumeral joint injection include osteoarthritis, adhesive capsulitis, rheumatoid arthritis and calcifications.

For the acromioclavicular joint, injection may be used for diagnosis and treatment of osteoarthritis and distal clavicular osteolysis.

Subacromial injections are useful for a range of conditions including adhesive capsulitis, sub-deltoid bursitis, impingement syndrome and rotator cuff tendinosis.

Pain in anterior region of the shoulder could be depend by an tendinosis of the biceps that can be treated with an injection.